Toxicology Pathway

Monday

32220 Opioids and Beyond: The Clinical Laboratory’s Role in the Opioid Epidemic

Toxicology testing for opioid compliance and abuse impacts both clinicians and laboratorians, with increased testing demands across the scope of care. Accurate interpretation of results is often a source of discussion and generates questions from the patient care team. This session will describe the clinical needs and testing approaches for opioid assessment, providing common challenges and solutions for both community and specialty hospital laboratories. The session will use an interactive, case-based approach. Learn more.

Tuesday

33108 Impact of Hormones on Drug Testing: From the Bench to the Bedside

Synthetic and endogenous hormones are known to affect not only physiology but also the pharmacology and efficacy of various drugs. People ingest, inject, and absorb synthetic hormones for a variety of reasons, ranging from performance enhancement for sports, as gender affirming hormonal therapies, contraception, symptom relief (menopause/endometriosis), and to replace or supplement endogenous hormone production. This session will survey the ways in which synthetic hormones influence drug pharmacology and how this can impact the practice of medicine. Learn more.

33219 Interactive Pain Management Case Studies: Clinician and Laboratory Perspectives

Pain is one of the most common reasons people seek care. Addiction and diversion of pain management medications is also a growing problem. As a result, physicians are using a variety of urine drug tests to provide objective measures to effectively manage pain patients, assess compliance, and detect diversion. This session will discuss the advantages and limitations of these assays and use interactive case studies to directly apply this knowledge to correctly interpret patient test results using live interactions between a clinician and laboratorians. Learn more.

Wednesday

44130 or 54230 Supporting Opioid Addiction Programs With Unexpected Testing—Ethanol Metabolite Test Development in an Appalachian Laboratory

The words “Opioid Addiction Program” evoke thoughts of standard drug screening approaches, but in a setting where complete abstinence is the goal, even markers for ethanol consumption have relevance. This session will describe how we built and implemented a mass spectrometry method for the glucuronide and sulfate metabolites of ethanol in urine. Learn more.

34109 Moving Beyond Immunoassays for the Poisoned Patient: Analytical Approaches and Interactive Case Studies

Urine toxicology testing has significant limitations when a patient presents with a potential overdose or poisoning. Many illicitly manufactured drugs and novel psychoactive substances, including synthetic amphetamines, cannabinoids, and opioids, such as fentanyl analogs, are not detected by routine drug testing. This interactive session will emphasize how to effectively communicate with clinicians for further testing, describe analytical tools used for monitoring the poisoned patient, and highlight the complexity of the current overdose epidemic in the United States through interactive case studies. Learn more.

Thursday

35103 Artery Hot Topics 2019

Using AACC’s online forum, Artery, as a metric, we have identified three common areas of ambiguity facing today’s clinical laboratorians: individualized quality control plans, oral glucose tolerance testing, and drugs of abuse immunoassay screening. Relevant to each of these challenges, this session will provide essential scientific background, current regulations and/or practice guidelines, and practical opportunities for resolution. Learn more.